NOT KNOWN FACTUAL STATEMENTS ABOUT PHENOBARBITAL

Monitor Closely (1)phenobarbital will lessen the level or effect of losartan by affecting hepatic/intestinal enzyme CYP3A4 metabolism.two. Corticosteroids: Phenobarbital seems to improve the metabolism of exogenous corticosteroids almost certainly in the induction of hepatic microsomal enzymes. Patients stabilized on corticosteroid therapy could in